• Schizophrenia is a neurodegenerative disorder characterized by various symptoms such as disturbances in information processing and cognitive impairment. Among the characteristics of this disease, NEUROFIT proposes models inducing cognitive disturbances (poor working memory, concentration troubles…) and hyperactivity (agitation).


    D-amphetamine enhances the release of dopamine in the central nervous system (CNS) and induces locomotor activation. Developing reliable, predictive animal models for complex psychiatric disorders, such as schizophrenia, is essential to increase our understanding of the neurobiological basis of the disorder and for the development of novel drugs.

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