Animal model for Rheumatoid Arthritis: Pristane induced arthritis in rat

Newsletter # 31



Animal models

Pristane-induced arthritis (PIA) is a preclinical model of arthritis that exhibits features of human rheumatoid arthritis (RA) such as symmetry of inflammation, chronic and relapsing course of disease, infiltration of T cells, and erosive destruction of cartilagenous peripheral joints. It is largely implemented to evaluate the mechanisms of inflammatory joint disease and also to test the efficiency of new anti-arthritic therapy.

NEUROFIT offers rapid, robust and validated PIA model in Dark-Agouti rats.


NEUROFIT offers a range of validated in vitro and in vivo screening tests for psychiatry and neurology.

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