• Amyotrophic lateral sclerosis (also called Lou Gehrig’s disease or Charcot disease) is a neurodegenerative disease characterized by the gradual degeneration of motor neurons causing ascending paralysis and leading to death.

    Nerve conductions and electromyography studies (also called electrodiagnostic testing) are widely used clinical practices for the assessment of symptoms resulting from nerve injury or muscle pathology. This clinical tool is also very useful in preclinical practice for monitoring peripheral nerve or muscle function, as for example in ALS disease models where it represents valuable translational medicine data.