Beam walking

  • Presentation


    Rats walk across an elevated 2.5m long beam graduated every 50cm.
    Successful walkg every 50cm is scored with 1 point. Misplacement is scored with -1.

    Rats with delayed motor initiative are those that do not move within the 120s after the initiation of the test and thus are considered having limb akinesia.

  • Compound testing


    Compounds acting on sensori-motor deficits are usually evaluated in this test but other treatments could also be considered. Please feel free to contact us to discuss the feasibility of your study.
  • Endpoints


    Prevalence of akinesia
    Walking score

  • NAC treatment markedly improved the motor deficit observed in 6-OHDA hemiparkinsonian rats



  • The prevalence of Akinesia was markedly high in 6-OHDA hemiparkinsonian rats.
    In addition, 6-OHDA hemiparkinsonian rats showed poor beam walking performance.



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