Hot plate

  • Presentation

    The hot-plate test consists in a thermal pain measurement. In this test, the animal is placed on a heated-plate to measure his thermal pain reflexes which are characterized either by withdrawal of the paw or by licking. This model has been implemented at Neurofit to evaluate the efficacy of your anti-inflammatory compounds or pain killers.

  • Compound testing

    Pain killers or anti-inflammatory drugs are usually tested in this model but other treatments could also be considered. Please feel free to contact us to discuss the feasibility of your study.
  • Endpoints

    Withdrawal or licking latency (s) in the hot-plate test.
  • Morphine dose response

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