Multiple sclerosis (MS), an inflammatory, autoimmune and demyelinating disease of the central nervous system, affects about 2.5 million people worldwide. Relapsing-remitting MS (RRMS) is the most common disease course at the time of diagnosis. Approximately 85-90% of individuals with MS are initially diagnosed with RRMS. MS is studied in the animal model experimental autoimmune encephalomyelitis (EAE). However, very limited data are available in the literature about EAE model that closely mimics the clinical symptoms of RRMS.