Cylinder test (limb asymmetry use)

  • Presentation


    Forelimb contacts with the wall of an open-top, clear plastic cylinder while rearing are counted during 2 min period.
    The percentage of use of the affected forelimb (contralateral) is calculated as index of motor function in this test.

  • Compound testing


    Compounds acting on sensori-motor deficits are usually evaluated in this test but other treatments could also be considered. Please feel free to contact us to discuss the feasibility of your study.
  • Endpoints


    % of use of the contralateral paw

  • NAC treatment markedly improved the contralateral forelimb motor deficit observed in 6-OHDA hemiparkinsonian rats.

  • 6-OHDA hemiparkinsonian rats showed dramatic motor deficit in the contralateral forelimb.

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