Newsletter # 42
Triple immunofluorescence images of neurons (nuclei stained in blue), microglia (green),and astrocytes (red) in LPS-activated cocultures.
|In-vivo disease-relevant mechanisms|
|Drug-screening oriented assay|
Release of neurotoxic factor such as nitric oxide (NO) in LPS-activated cocultures.
Resveratrol and dexamethasone inhibit in dose-dependent manner the NO release by LPS-activated cocultures.
Neuronal death in LPS-activated cocultures.
Resveratrol and dexamethasone dose-dependently inhibit neuronal death in LPS-activated cocultures.
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In addition to our Cellular models, consult also our Animal models in THERAPEUTIC AREA and TESTS sections at our website