Translational model of Multiple Sclerosis - Remittance and disease relapse

Newsletter # 59

Animal models

Multiple Sclerosis (MS) is a chronic disease of the central nervous system, which predominantly affects young adults. A few medications can be used to treat the symptoms but they have limited efficacy or safety. Thus, the search for new and more effective treatments for MS remains an area of great focus.

NEUROFIT offers several preclinical models relevant for drug testing in MS. The rat model highlighted herein is translatable to clinical setting of Relapsing/Remitting Multiple Sclerosis (RR-MS). Similarly to MS patients, affected rats show dexamethasone-sensitive disease relapse.

NEUROFIT offers several specific and validated models of Multiple Sclerosis. Here we propose the proof of internal validation of Relapsing/Remitting Multiple Sclerosis (RR-MS) model in the rat.

NEUROFIT offers a range of validated in vitro and in vivo screening tests for psychiatry and neurology.

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